Central pain after pontine infarction is associated with changes in opioid receptor binding: a PET study with 11C-diprenorphine.
نویسندگان
چکیده
Using 18F-fluorodeoxyglucose and 11C-diprenorphine positron emission tomography (PET), we investigated alterations in glucose metabolism and opioid receptor binding in a patient with central poststroke pain, which developed after a small pontine hemorrhagic infarction. In comparison with normal databases, reduced 11C-diprenorphine binding was more accentuated than the hypometabolism on the lateral cortical surface contralateral to the symptoms, and a differential abnormal distribution between the tracers was seen in pain-related central structures. These results show that 11C-diprenorphine PET provides unique information for the understanding of central poststroke pain.
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عنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 20 4 شماره
صفحات -
تاریخ انتشار 1999